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Cat No. | Product Name | Synonyms | Targets |
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T6052 | GW 441756 | Apoptosis , Raf , Trk receptor , CDK | |
GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM. | |||
T11861 | LM11A-31 dihydrochloride | Others | |
LM11A-31 dihydrochloride is a water-soluble, non-peptide with high blood-brain barrier permeability.LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagoni... | |||
T9272 | Xaliproden hydrochloride | Dopamine Receptor , 5-HT Receptor | |
Xaliproden is a compound that mimics the effects of nerve growth factor and is also a serotonin 5-HT1A receptor agonist. | |||
T76813 | Bedinvetmab | ||
Bedinvetmab (ZTS-00508841), a canine monoclonal antibody (mAb) designed to target nerve growth factor (NGF), prevents NGF from interacting with its receptors, tropomyosin receptor kinase A (trkA) and p75 neurotrophin rec... | |||
T63346 | TRK-IN-18 | ||
TRK-IN-18 is a potent inhibitor of TRK. Among them are promyosin-related kinases (Trks), a family of receptor tyrosine kinases activated by neurotrophic factors, a group of soluble growth factors containing nerve growth ... | |||
T63965 | Bepotastine tosylate | ||
Bepotastine tosylate is a selective, orally active second-generation histamine H1 receptor antagonist that exhibits an inhibitory effect on histamine-mediated upregulation of nerve growth factor (NGF) expression. conjunc... | |||
T62561 | TRK-IN-17 | ||
TRK-IN-17 is a potent inhibitor of TRK. Among them is promyosin-related kinase (Trks), a member of the receptor tyrosine kinase family, which is activated by neurotrophic factors. Neurotrophic factors are a group of solu... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2S0843 | Negletein | 7-O-Methylbaicalein,Baicalein-7-methylether | IL Receptor , TNF , NOS , Interleukin |
1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02614 | NGFR/p75NTR Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
NGFR/p75NTR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.6 kDa and the accession number is P08138. | |||
TMPY-06973 | NGFR/p75NTR Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
NGFR/p75NTR Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.03 kDa and the accession number is XP_005583674.1. | |||
TMPY-06959 | NGFR/p75NTR Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
NGFR/p75NTR Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.34 kDa and the accession number is P07174. | |||
TMPY-04646 | NGFR/p75NTR Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 Cells |
NGFR/p75NTR Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.8 kDa and the accession number is XP_008269543.1. | |||
TMPY-04831 | NGFR/p75NTR Protein, Rabbit, Recombinant (hFc) | Rabbit | HEK293 Cells |
NGFR/p75NTR Protein, Rabbit, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.1 kDa and the accession number is XP_008269543.1. | |||
TMPY-02588 | NGFR/p75NTR Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
NGFR/p75NTR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.6 kDa and the accession number is Q9Z0W1. | |||
TMPY-02541 | NGFR/p75NTR Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
NGFR/p75NTR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is Q9Z0W1. | |||
TMPY-02615 | NGFR/p75NTR Protein, Human, Recombinant (His) | Human | HEK293 Cells |
NGFR/p75NTR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is P08138. | |||
TMPJ-01468 | Pro-Beta NGF Protein, Human, Recombinant | Human | E. coli |
The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite... | |||
TMPJ-00135 | BDNF Protein, Human/Murine/Rat, Recombinant | Human,Mouse,Rat | E. coli |
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. I... | |||
TMPK-00774 | TrkA Protein, Human, Recombinant (aa 33-417, His) | Human | HEK293 Cells |
TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces receptor autophosphorylation and activation of intracellular signa... |